TO DETERMINE WHETHER ABNORMAL UMBILICAL ARTERY DOPPLER IS A PREDICTOR OF ADVERSE PERINATAL OUTCOME IN PATIENTS WITH PRE ECLAMPSIA AT THE LAGOS STATE UNIVERSITY TEACHING HOSPITAL, IKEJA
BACKGROUND: Doppler velocimetry studies of fetal umbilical artery can provide important information regarding fetal wellbeing. The present study was undertaken to determine whether abnormal umbilical artery Doppler waveform is a predictor of perinatal outcome in patients with pre-eclampsia in the obstetrics and gynecology department of Lagos state university teaching hospital Ikeja, Lagos.
METHODS: In this prospective cross-sectional study, abnormal doppler waveforms of the umbilical artery velocity and adverse perinatal outcome of (100) patients with preeclampsia were evaluated after 28weeks gestation.
RESULTS: Among the 100 subjects studied, 42 of them had mild preeclampsia while 58 had severe preeclampsia. Patients with severe preeclampsia where noticed to have more abnormal doppler waveforms and higher values of doppler indices as compared with those with mild preeclampsia. (P- Value <0.001). Patients with abnormal umbilical artery doppler waveform patterns were significantly associated with adverse perinatal outcome than those with normal waveform pattern. (P- Value <0.001). Abnormal doppler velocimetry was found to be an independent risk factor for adverse perinatal outcome with an odds ratio of 10.3 and P-value <0.001.
CONCLUSION: Doppler can be considered as one of the most important non- invasive technique to assess fetomaternal circulation. Due to its feasibility and safety, it can be used as antepartum surveillance in patients with preeclampsia to determine pregnancy outcome and also formulate plan of management for optimum fetal outcome.