EFFECT OF HYOSINE NEBUTYLBROMIDE IN THE DURATION OF LABOUR IN TERM PREGNANCIES IN NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL NNEWI SOUTH EAST NIGERIA
Background: labour is ideally a joyous experience but can be associated with
fetomaternal complications when prolonged thus any safe measure to prevent pronged labour is a well development for both the parturients and care givers.
Objectives: To evaluate the effect of hyocine n-butyl bromide (HBB) on the duration of the first stage of labour in term pregnancies in NAUTH Nnewi. Methods: This is a double blind randomized trial involving 124 parturients who presented to the Labour ward of Nnamdi Azikiwe university teaching hospital at term in active phase of labour. They were randomly given an intramuscular injection of either 40mg of HBB or 2mls of water for injection as a placebo. The
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effect of HBB on duration of the stages of labour, maternal and neonatal complications were then evaluated.
Results: The mean duration of the first stage of labour was noted to be shorter in HBB group for both the primigravidas (246.56+21.86 against 391.81+56.57 minutes for control) and for multiparous (205.88+17.80 against 323.83+15.99 for control). There were no significant change in the duration of second and third stages of labour for classes of parturients in both groups. There no significant changes in the mode of delivery or in maternal or neonatal out come in both groups of partnturients. Conclusions: Hyoscine n-butyl bromide is effective in reducing the first stage of labour without adverse maternal or neonatal outcome.